Frequently asked questions
Eyevistar® is a standardized marigold-derived formulation containing 20% lutein and 4% zeaxanthin. Its product-specific research includes ARPE-19 retinal cell testing and an in-vivo study of retinal oxidative stress, carotenoid deposition and lipofuscin accumulation.
Product
What is Eyevistar®?+
Eyevistar® is a natural standardized formulation derived from marigold extract. It contains lutein at 20% and zeaxanthin at 4% and is designed for nutraceutical formulations that support retinal integrity, antioxidant protection and long-term visual performance.
What is Eyevistar® standardized to?+
Eyevistar® is standardized to 20% lutein and 4% zeaxanthin. It is a lutein and zeaxanthin formulation manufactured by Star Hi Herbs Pvt. Ltd.
What is the botanical source of Eyevistar®?+
Eyevistar® is derived from marigold. Marigold, Tagetes erecta L., is a natural commercial source of lutein and zeaxanthin used in eye-health nutraceutical formulations.
What are the main bioactive compounds in Eyevistar®?+
The two principal bioactive carotenoids are lutein and zeaxanthin. Both selectively accumulate in the macular region of the retina and contribute to the macular pigment.
How is Eyevistar® different from a generic marigold extract?+
Eyevistar® provides a defined combination of 20% lutein and 4% zeaxanthin together with product-specific preclinical research evaluating retinal cell viability, UV-induced oxidative stress, A2E, lipofuscin, antioxidant biomarkers and retinal carotenoid deposition. An Eyevistar-specific patent is not currently identified, so no patented-product claim is made.
Why are lutein and zeaxanthin important for eye health?+
They form part of the macular pigment. Two principal functions are described: filtering high-energy blue light before it reaches the photoreceptors, and helping neutralize reactive oxygen species associated with oxidative damage.
Research and efficacy
What research has been conducted on Eyevistar®?+
Eyevistar® has been evaluated in ARPE-19 retinal pigment epithelial cells and in a 42-day high-fat-diet animal model. A double-blind, placebo-controlled human study is ongoing; human results are not yet available.
What did the ARPE-19 cell study show?+
Eyevistar® maintained 94.08% cell viability at 1,000 µg/mL and increased ARPE-19 cell proliferation by 33.59%, 46.15% and 62.31% at 125, 250 and 500 µg/mL respectively.
Did Eyevistar® protect retinal cells from UV-induced stress?+
Under the reported laboratory conditions, UV exposure reduced viability to approximately 50.98%. Eyevistar® increased viability of UV-exposed ARPE-19 cells to 81.19% at 250 µg/mL and 100.64% at 500 µg/mL. These are laboratory findings, not human clinical outcomes.
Does Eyevistar® affect A2E and lipofuscin accumulation?+
In the ARPE-19 cell model, Eyevistar® reduced UV-induced A2E accumulation. Transmission electron microscopy also showed fewer lipofuscin granules in Eyevistar-treated cells than in UV-exposed untreated cells.
What did the in-vivo Eyevistar® study show?+
In a 42-day animal study using 2.5, 5 and 10 mg/kg daily doses, Eyevistar® was associated with improved antioxidant markers, reduced retinal lipofuscin, increased plasma and macular carotenoid levels, reduced retinal stress biomarkers and preservation of retinal architecture. The strongest effects were generally observed at 10 mg/kg.
What is the clinically studied human dose of Eyevistar®?+
A validated human dose is not yet established. Animal-study doses should not be used directly as finished-product human serving levels.
How long does Eyevistar® take to work?+
The available research does not establish a human onset-of-effect period. Laboratory assessments lasted approximately 24 to 72 hours, while the animal study lasted 42 days.
Safety and regulatory
Is Eyevistar® safe?+
Eyevistar® maintained more than 94% ARPE-19 cell viability at concentrations up to 1,000 µg/mL in the reported laboratory assessment. Completed human tolerability and adverse-event results are not yet available.
Is Eyevistar® Non-GMO, Kosher, Halal, vegan, gluten-free or allergen-free?+
Product-specific certification and declaration status should be confirmed from the latest Eyevistar® quality and regulatory documents.
Is Eyevistar® approved in the United States, European Union or India?+
Market-specific approval or authorization is not currently established. Regulatory status depends on ingredient form, intended use, daily intake, finished-product category and the laws of the destination market.
Formulation
Can Eyevistar® be used in capsules, gummies or beverages?+
Suitability for capsules, tablets, gummies, powders, softgels and beverages should be confirmed through the current technical specification and application testing. Water dispersibility, heat stability, flavour and colour performance data are not currently available.
What use level should formulators choose?+
The use level should be selected according to the intended lutein and zeaxanthin delivery per serving, the final format, local regulations and the validated human clinical dose once available.
What ingredients can Eyevistar® be combined with?+
Co-ingredient combinations have not been evaluated in the current research. Compatibility with vitamins, minerals, omega-3 fatty acids, botanical extracts or other carotenoids should be confirmed through stability and formulation testing.
Commercial
What is the minimum order quantity for Eyevistar®?+
Contact the Star Hi Herbs commercial team to confirm the current minimum order quantity, packaging configuration, lead time and destination-specific terms.
Can I request an Eyevistar® sample?+
Sample availability, quantity and shipping terms can be confirmed through the Eyevistar® sample-request or contact form.
What is the shelf life of Eyevistar®?+
Shelf life and recommended storage conditions should be taken from the current approved product specification, Certificate of Analysis and stability documentation.
What documentation is available?+
A research summary and detailed preclinical research report are available. Availability of commercial documents such as the specification sheet, COA, safety data sheet, allergen statement, Non-GMO declaration, manufacturing flow chart and certification documents should be confirmed with the quality team.
Can customers use the Eyevistar® name or logo on finished products?+
Written authorization is required before using the Eyevistar® name or logo on packaging or marketing materials. Minimum inclusion level, artwork approval and licensing conditions are agreed as part of the trademark licence.
More detail on Eyevistar®
Still have a question?
Our technical and regulatory teams can answer market-specific, formulation and documentation questions directly.